Duocarmycin Analog

• CAS Number:

  372954-15-9

• UNSPSC Description:

  Duocarmycin Analog is an analog of Duocarmycin, and used as an DNA alkylator and ADC cytotoxin[1].

• Target Antigen:

  ADC Cytotoxin; DNA Alkylator/Crosslinker

• Type:

  ADC Related

• Related Pathways:

  Antibody-drug Conjugate/ADC Related;Cell Cycle/DNA Damage

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/duocarmycin-analog.html

• Purity:

  95.85

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C(OC(C)(C)C)NC1=CC=C(C(NC2=CC3=C(NC(C(N4C[C@@H](CCl)C5=C4C=C(O)C6=CC=CC=C56)=O)=C3)C=C2)=O)C=C1

• Molecular Weight:

  611.09

• References & Citations:

  [1]Boger, Dale L. CBI ANALOGUES OF CC-1065 AND THE DUOCARMYCINS. WO2003022806A2

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  -20°C, 3 years (Powder)

• Clinical Information:

  No Development Reported