L-Selectin/CD62L Extracellular Domain

• Description:

  L-Selectin/CD62L Extracellular Domain_x000D_ Catalog number: B2016838_x000D_ Lot number: Batch Dependent_x000D_ Expiration Date: Batch dependent_x000D_ Amount: 50 µg_x000D_ Molecular Weight or Concentration: 61 kDa_x000D_ Supplied as: Powder_x000D_ Applications: a molecular tool for various biochemical applications_x000D_ Storage: -80°C_x000D_ Keywords: CD62 Antigen-like Family Member L, LAM1, LECAM1, Leukocyte-endothelial Cell Adhesion Molecule 1_x000D_ Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ References:_x000D_ 1: Stoddart JH Jr, Jasuja RR, Sikorski MA, von Andrian UH, Mier JW. Protease-resistant L-selectin mutants. Down-modulation by cross-linking but not cellular activation J Immunol. 1996 Dec 15;157(12):5653-9._x000D_ 2: Spencer M, Max N, Ireland J, Zou Z, Wang R, Sun P. Over-expression of a human CD62L ecto-domain and a potential role of RNA pseudoknot structures in recombinant protein expression Protein Expr Purif. 2017 Dec;140:65-73._x000D_ 3: Nishimura Y, Shimojima M, Tohya Y, Miyazawa T. Molecular cloning of a cDNA encoding the feline CD62L J Vet Med Sci. 2007 Jan;69(1):81-4._x000D_ 4: Ivetic A, Hoskins Green HL, Hart SJ. L-selectin: A Major Regulator of Leukocyte Adhesion, Migration and Signaling Front Immunol. 2019 May 14;10:1068._x000D_ 5: Drescher HK, Schippers A, Rosenhain S, Gremse F, Bongiovanni L, Bruin A, Eswaran S, Gallage SU, Pfister D, Szydlowska M, Heikenwalder M, Weiskirchen S, Wagner N, Trautwein C, Weiskirchen R, Kroy DC. L-Selectin/CD62L is a Key Driver of Non-Alcoholic Steatohepatitis in Mice and Men Cells. 2020 Apr 29;9(5):1106._x000D_ 6: Golubovskaya V, Wu L. Different Subsets of T Cells, Memory, Effector Functions, and CAR-T Immunotherapy Cancers (Basel). 2016 Mar 15;8(3):36._x000D_ 7: Segura J, He B, Ireland J, Zou Z, Shen T, Roth G, Sun PD. The Role of L-Selectin in HIV Infection Front Microbiol. 2021 Sep 29;12:725741._x000D_ 8: Cichocki F, Zhang B, Wu CY, Chiu E, Day A, O'Connor RS, Yackoubov D, Simantov R, McKenna DH, Cao Q, Defor TE, Janakiram M, Wangen R, Cayci Z, Snyder N, Kumar A, Grzywacz B, Hwang J, Geffen Y, Miller JS, Maakaron J, Bachanova V. Nicotinamide enhances natural killer cell function and yields remissions in patients with non-Hodgkin lymphoma Sci Transl Med. 2023 Jul 19;15(705):eade3341._x000D_ 9: Watson HA, Durairaj RRP, Ohme J, Alatsatianos M, Almutairi H, Mohammed RN, Vigar M, Reed SG, Paisey SJ, Marshall C, Gallimore A, Ager A. L-Selectin Enhanced T Cells Improve the Efficacy of Cancer Immunotherapy Front Immunol. 2019 Jun 12;10:1321._x000D_ 10: Klinger A, Gebert A, Bieber K, Kalies K, Ager A, Bell EB, Westermann J. Cyclical expression of L-selectin (CD62L) by recirculating T cells Int Immunol. 2009 Apr;21(4):443-55. _x000D_ _x000D_ Products Related to L-Selectin/CD62L Extracellular Domain can be found at Proteins

• Short Description:

  Catalog Number: B2016838 (50 µg)_x000D_ L-Selectin/CD62L Extracellular Domain is a high quality cell adhesion molecule that is expressed on the surface of leukocytes, including lymphocytes. It plays a key role in the immune response by mediating the adhesion of leukocytes to endothelial cells in the blood vessels, allowing them to migrate to sites of inflammation or infection. The extracellular domain of L-Selectin/CD62L refers to the portion of the protein that is located outside the cell membrane. This product has been used as a molecular tool for various biochemical applications. It has also been used in a wide array of other chemical and immunological applications. Custom bulk amounts of this product are available upon request._x000D_ _x000D_

• Weight:

  0.15

• Length:

  2

• Width:

  0.5

• Height :

  0.5