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L-Selectin (CD62L)

CAT: 0209-103-M108Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0209-103-M108Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
The Selectin family is comprised of three members, E-Selectin, L-Selectin, and P-Selectin. E-Selectin [endothelial leukocyte adhesion molecule-1 (ELAM-1), CD62E] is transiently expressed on vascular endothelial cells in response to IL-1 beta and TNF-alpha. The human and rat proteins share approximately 67% amino acid sequence identity. The mouse and rat proteins share approximately 78% amino acid sequence identity. L-Selectin is expressed constitutively on a wide variety of leukocytes. Two forms of L-Selectin have been reported, apparently arising as a result of post-translational modifications. Human and mouse L-Selectin share 76% amino acid sequence identity. Human P-Selectin (GMP-140, LECAM-3, PADGEM, CD62P) is expressed by activated platelets and endothelial cells. The extracellular domains of human and mouse P-Selectin share approximately 73% amino acid sequence identity.
Synonyms
Sell; Lnhr; CD62L; Ly-22; Lyam1; Ly-m22; Lyam-1; LECAM-1; AI528707; L-selectin; Leukocyte Selectin, LAM-1, LECCAM-1, TQ1, Leu-8, MEL-14 antigen, DREG, lymph node homing receptor
NCBI Gene ID
20343
UniProt
P18337
Accession Number
NP_035476.1
Accession Number mRNA
NM_011346.2
Chromosomal Location
1 H2.2; 1 86.6 cM
Reactivity
Anti-Mouse
Cross Reactivity
Mouse
Target Antigen
Mouse B lymphocyte cells
Clone
(#MAB0709)
Applications
IHC (P), FC
Purification Method
Protein A/G chromatography
Assay Protocol
Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Form
Lyophilized
Buffer
PBS
Reconstitution
PBS (sterile)
Storage Conditions
Lyophilized samples are stable for 2 years from date of receipt when stored at -20°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.
Host or Source
Rat
Isotype
IgG2

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