L-Selectin Antibody / CD62L

L-Selectin Antibody / CD62L

• Description: Selectins, also designated CD62 antigens, comprise a family of carbohydrate-binding proteins involved in mediating cellular interactions with leukocytes. L-Selectin (also designated LECAM-1 or CD62L) is expressed on the majority of B and naive T cells and on most monocytes, neutrophils and eosinophils. L-Selectin interacts with specific carbohydrates expressed by activated endothelial cells. P-Selectin (also designated GMP-140 or CD62P), expressed on activated platelets and endothelial cells, and E-Selectin (also designated ELMA-1 or CD62E), expressed on endothelial cells, exhibit overlapping ligand specificities. Both recognize sialyl-Le (x) as a ligand and bind to specific carbohydrates on neutrophils and monocytes.
• CAS Number: 9007-83-4
• UniProt: P14151
• Host: Mouse
• Immunogen: Supernatant from phorbol myristic acid activated human peripheral blood leukocytes was used as the immunogen for the L-Selectin antibody.
• Clonality: Monoclonal
• Isotype: IgG1 κ
• Applications: ELISA, FACS, WB
• Format: Purified
• Buffer: 0.2 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
• Reconstitution: Store the L-Selectin antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
• Limitations: This L-Selectin antibody is available for research use only.