FGFR1 Extracellular Domain Human Recombinant

• Description:

  FGFR1 Extracellular Domain Human Recombinant _x000D_ Catalog number: B2016891_x000D_ Lot number: Batch Dependent_x000D_ Expiration Date: Batch dependent_x000D_ Amount: 50 µg_x000D_ Molecular Weight or Concentration: 31 kDa_x000D_ Supplied as: Powder_x000D_ Applications: a molecular tool for various biochemical applications_x000D_ Storage: -80°C_x000D_ Keywords: Basic Fibroblast Growth Factor Receptor 1, bFGF-R-1, BFGFR, CD331, Fibroblast Growth Factor Receptor 1, FGFBR, FLT2, Fms-like Tyrosine Kinase 2_x000D_ Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ References:_x000D_ 1: Martínez-Torrecuadrada J, Cifuentes G, López-Serra P, Saenz P, Martínez A, Casal JI. Targeting the extracellular domain of fibroblast growth factor receptor 3 with human single-chain Fv antibodies inhibits bladder carcinoma cell line proliferation Clin Cancer Res. 2005 Sep 1;11(17):6280-90._x000D_ 2: Stachowiak MK, Maher PA, Stachowiak EK. Integrative nuclear signaling in cell development--a role for FGF receptor-1 DNA Cell Biol. 2007 Dec;26(12):811-26._x000D_ 3: Jurek PM, ZabÅ‚ocki K, WaÅ›ko U, Mazurek MP, Otlewski J, JeleÅ„ F. Anti-FGFR1 aptamer-tagged superparamagnetic conjugates for anticancer hyperthermia therapy Int J Nanomedicine. 2017 Apr 11;12:2941-2950._x000D_ 4: Sleeman M, Fraser J, McDonald M, Yuan S, White D, Grandison P, Kumble K, Watson JD, Murison JG. Identification of a new fibroblast growth factor receptor, FGFR5 Gene. 2001 Jun 27;271(2):171-82._x000D_ 5: Gorbenko O, Ovcharenko G, Volkova D, Mayilo D, Gaman N, Khozhayenko Y, Usenko V, Gout I, Filonenko V. Monoclonal antibodies with selective specificity towards different glycosylation isoforms of FGFR1 Hybridoma (Larchmt). 2009 Aug;28(4):287-93._x000D_ 6: Ryu EK, Cho KJ, Kim JK, Harmer NJ, Blundell TL, Kim KH. Expression and purification of recombinant human fibroblast growth factor receptor in Escherichia coli Protein Expr Purif. 2006 Sep;49(1):15-22._x000D_ 7: Hanneken A, Maher PA, Baird A. High affinity immunoreactive FGF receptors in the extracellular matrix of vascular endothelial cells--implications for the modulation of FGF-2 J Cell Biol. 1995 Mar;128(6):1221-8._x000D_ 8: Levi E, Fridman R, Miao HQ, Ma YS, Yayon A, Vlodavsky I. Matrix metalloproteinase 2 releases active soluble ectodomain of fibroblast growth factor receptor 1 Proc Natl Acad Sci U S A. 1996 Jul 9;93(14):7069-74._x000D_ 9: Werner S, Duan DS, de Vries C, Peters KG, Johnson DE, Williams LT. Differential splicing in the extracellular region of fibroblast growth factor receptor 1 generates receptor variants with different ligand-binding specificities Mol Cell Biol. 1992 Jan;12(1):82-8._x000D_ 10: Suzuki Y, Kuzina E, An SJ, Tome F, Mohanty J, Li W, Lee S, Liu Y, Lax I, Schlessinger J. FGF23 contains two distinct high-affinity binding sites enabling bivalent interactions with α-Klotho Proc Natl Acad Sci U S A. 2020 Dec 15;117(50):31800-31807. _x000D_ _x000D_ Products Related to FGFR1 Extracellular Domain Human Recombinant can be found at Proteins

• Short Description:

  Catalog Number: B2016891 (50 µg)_x000D_ FGFR1 Extracellular Domain Human Recombinant is a high quality protein that is produced in a laboratory setting using genetic engineering techniques. In this case, the protein is the extracellular domain of the human Fibroblast Growth Factor Receptor 1 (FGFR1). The extracellular domain of a receptor is the part of the protein that is located outside of the cell and is involved in binding to specific ligands or molecules to initiate signaling pathways within the cell. This product has been used as a molecular tool for various biochemical applications. It has also been used in a wide array of other chemical and immunological applications. Custom bulk amounts of this product are available upon request._x000D_ _x000D_

• Weight:

  0.15

• Length:

  2

• Width:

  0.5

• Height :

  0.5

• CAS Number:

  9000-83-3