Human Recombinant ALK7 Extracellular Domain

• Description:

  Human Recombinant ALK7 Extracellular Domain _x000D_ Catalog number: B2017057_x000D_ Lot number: Batch Dependent_x000D_ Expiration Date: Batch dependent_x000D_ Amount: 100 µg_x000D_ Molecular Weight or Concentration: 36.6 kDa_x000D_ Supplied as: Powder_x000D_ Applications: a molecular tool for various biochemical applications_x000D_ Storage: -80°C_x000D_ Keywords: Activin Receptor-like Kinase , Activin Receptor Type-1C, ACVR1C_x000D_ Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ References:_x000D_ 1: Lotinun S, Pearsall RS, Horne WC, Baron R. Activin receptor signaling: a potential therapeutic target for osteoporosis Curr Mol Pharmacol. 2012 Jun;5(2):195-204._x000D_ 2: Kumar R, Grinberg AV, Li H, Kuo TH, Sako D, Krishnan L, Liharska K, Li J, Grenha R, Maguire MC, Briscoe SD, Pearsall RS, Herrin BR, Suragani RNVS, Castonguay R. Functionally diverse heteromeric traps for ligands of the transforming growth factor-β superfamily Sci Rep. 2021 Sep 15;11(1):18341._x000D_ 3: Calvanese L, Sandomenico A, Caporale A, Focà A, Focà G, D'Auria G, Falcigno L, Ruvo M. Conformational features and binding affinities to Cripto, ALK7 and ALK4 of Nodal synthetic fragments J Pept Sci. 2015 Apr;21(4):283-93._x000D_ 4: Munir S, Xu G, Wu Y, Yang B, Lala PK, Peng C. Nodal and ALK7 inhibit proliferation and induce apoptosis in human trophoblast cells J Biol Chem. 2004 Jul 23;279(30):31277-86._x000D_ 5: Bondestam J, Huotari MA, Morén A, Ustinov J, Kaivo-Oja N, Kallio J, Horelli-Kuitunen N, Aaltonen J, Fujii M, Moustakas A, Ten Dijke P, Otonkoski T, Ritvos O. cDNA cloning, expression studies and chromosome mapping of human type I serine/threonine kinase receptor ALK7 (ACVR1C) Cytogenet Cell Genet. 2001;95(3-4):157-62._x000D_ 6: Watanabe R, Yamada Y, Ihara Y, Someya Y, Kubota A, Kagimoto S, Kuroe A, Iwakura T, Shen ZP, Inada A, Adachi T, Ban N, Miyawaki K, Sunaga Y, Tsuda K, Seino Y. The MH1 domains of smad2 and smad3 are involved in the regulation of the ALK7 signals Biochem Biophys Res Commun. 1999 Jan 27;254(3):707-12._x000D_ 7: Xu G, Zhou H, Wang Q, Auersperg N, Peng C. Activin receptor-like kinase 7 induces apoptosis through up-regulation of Bax and down-regulation of Xiap in normal and malignant ovarian epithelial cell lines Mol Cancer Res. 2006 Apr;4(4):235-46._x000D_ 8: Kim BC, van Gelder H, Kim TA, Lee HJ, Baik KG, Chun HH, Lee DA, Choi KS, Kim SJ. Activin receptor-like kinase-7 induces apoptosis through activation of MAPKs in a Smad3-dependent mechanism in hepatoma cells J Biol Chem. 2004 Jul 2;279(27):28458-65._x000D_ 9: Tian RH, Yang S, Zhu ZJ, Wang JL, Liu Y, Yao C, Ma M, Guo Y, Yuan Q, Hai Y, Huang YR, He Z, Li Z. NODAL secreted by male germ cells regulates the proliferation and function of human Sertoli cells from obstructive azoospermia and nonobstructive azoospermia patients Asian J Androl. 2015 Nov-Dec;17(6):996-1005._x000D_ 10: Finkenzeller G, Stark GB, Strassburg S. Growth differentiation factor 11 supports migration and sprouting of endothelial progenitor cells J Surg Res. 2015 Sep;198(1):50-6. _x000D_ _x000D_ Products Related to Human Recombinant ALK7 Extracellular Domain can be found at Proteins

• Short Description:

  Catalog Number: B2017057 (100 µg)

• Weight:

  0.15

• Length:

  2

• Width:

  0.5

• Height:

  0.5

• Height :

  0.5

• CAS Number:

  9000-83-3