PD-1/PD-L1-IN-21

PD-1/PD-L1-IN-21

• CAS Number: 2158336-16-2
• UNSPSC Description: PD-1/PD-L1-IN-21 (Example 22) is a small-molecule inhibitor of the PD-1/PD-L1 protein-protein interaction. PD-1/PD-L1-IN-21 blocks PD-1/PD-L1 with the IC50 of 4.99 μM. PD-1/PD-L1-IN-21 can be used for the research of cancers, infectious diseases and autoimmune diseases[1].
• Target Antigen: PD-1/PD-L1
• Type: Reference compound
• Related Pathways: Immunology/Inflammation
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/pd-1-pd-l1-in-21.html
• Solubility: 10 mM in DMSO
• Smiles: CC[C@H](C)[C@@H](C(O)=O)NCC(C=C(C(OCC1=C(C(C2=CC=CC=C2)=CC=C1)Br)=C3)Cl)=C3OCC4=CN=CC=C4
• Molecular Weight: 623.96
• References & Citations: [1]Nicotinyl alcohol ether derivative, preparation method therefor, and pharmaceutical composition and uses thereof. WO2017202274A1.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported