PROTAC SMARCA2 degrader-19

CAT:
804-HY-169270
Size:
Inquire
  • Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
  • Dry Ice Shipment: No
PROTAC SMARCA2 degrader-19 - image 1

PROTAC SMARCA2 degrader-19

  • UNSPSC Description:

    PROTAC SMARCA2 degrader-19 (Compound 46) is a PROTAC degrader for SMARCA2, that degrades SMARCA2 in cell A549 and MV411 with a DC50 SMARCA4 in cell MV411 with a DC50 > 1000 nM[1].
  • Target Antigen:

    Epigenetic Reader Domain; PROTACs
  • Type:

    Reference compound
  • Related Pathways:

    Epigenetics;PROTAC
  • Applications:

    Cancer-programmed cell death
  • Field of Research:

    Cancer
  • Assay Protocol:

    https://www.medchemexpress.com/protac-smarca2-degrader-19.html
  • Smiles:

    OC1=C(C=CC=C1)C2=NN=C3NC=C(C4CCN(C5=NC=C([C@@H]6CC[C@H](CC6)C(N[C@@H](C(C)(C)C)C(N7[C@@H](C[C@H](C7)O)C(NCC8=CC=C(C9=C(C)N=CS9)C=C8)=O)=O)=O)C=N5)CC4)C3=C2
  • Molecular Weight:

    911.12
  • References & Citations:

    [1]Ji, et al., Smarca degraders and uses thereof. WO2020251972.
  • Shipping Conditions:

    Room temperature
  • Clinical Information:

    No Development Reported
  • CAS Number:

    2567913-00-0