PROTAC SMARCA2 degrader-19
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804-HY-169270
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PROTAC SMARCA2 degrader-19
UNSPSC Description:
PROTAC SMARCA2 degrader-19 (Compound 46) is a PROTAC degrader for SMARCA2, that degrades SMARCA2 in cell A549 and MV411 with a DC50 SMARCA4 in cell MV411 with a DC50 > 1000 nM[1].Target Antigen:
Epigenetic Reader Domain; PROTACsType:
Reference compoundRelated Pathways:
Epigenetics;PROTACApplications:
Cancer-programmed cell deathField of Research:
CancerAssay Protocol:
https://www.medchemexpress.com/protac-smarca2-degrader-19.htmlSmiles:
OC1=C(C=CC=C1)C2=NN=C3NC=C(C4CCN(C5=NC=C([C@@H]6CC[C@H](CC6)C(N[C@@H](C(C)(C)C)C(N7[C@@H](C[C@H](C7)O)C(NCC8=CC=C(C9=C(C)N=CS9)C=C8)=O)=O)=O)C=N5)CC4)C3=C2Molecular Weight:
911.12References & Citations:
[1]Ji, et al., Smarca degraders and uses thereof. WO2020251972.Shipping Conditions:
Room temperatureClinical Information:
No Development ReportedCAS Number:
2567913-00-0