ER-851

• UNSPSC Description:

  ER-851 is a selective AXL inhibitor with oral activity with IC50 of 100 nM. ER-851 has antitumor activity[1].

• Target Antigen:

  TAM Receptor

• Type:

  Reference compound

• Related Pathways:

  Protein Tyrosine Kinase/RTK

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/er-851.html

• Smiles:

  O=C(C(C(N1C2=NC=C(C)C=C2)=O)=CN(C3CCCC3)C1=O)NC(C=C4F)=CC=C4OC5=NC=NC6=C5CCN(CC7CCN(C)CC7)C6

• Molecular Weight:

  668.76

• References & Citations:

  [1]Tsukamoto S, et al. ER-851, a Novel Selective Inhibitor of AXL, Overcomes Resistance to Antimitotic Drugs. Mol Cancer Ther. 2023 Jan 3;22(1):12-24.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  2685738-33-2