DMP-851

CAT: 0804-HY-19281Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-19281Size:1 Each
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Description
DMP-851 is a cyclic urea HIV protease inhibitor, with a Ki of 0.021 nM. DMP-851 shows antiviral activity against laboratory strains of HIV-l and HIV-2 as well as against primary clinical isolates derived from Zidovudine (HY-17413) -resistant samples (A018C, E, WR 10983) [1].
CAS Number
[188978-02-1]
UNSPSC
12352005
Target
HIV; HIV Protease
Related Pathways
Anti-infection; Metabolic Enzyme/Protease
Field of Research
Infection
Smiles
O=C1N(CC2=CC3=C(NN=C3N)C=C2)[C@H](CC4=CC=CC=C4)[C@H](O)[C@@H](O)[C@@H](CC5=CC=CC=C5)N1CCCC
Molecular Formula
C31H37N5O3
Molecular Weight
527.66
References & Citations
[1]Rodgers JD, et al. Design and selection of DMP 850 and DMP 851: the next generation of cyclic urea HIV protease inhibitors. Chem Biol. 1998 Nov;5 (11) :R312.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 1
Isoform
HIV-1; HIV-2

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