DPI-3290

CAT: 0804-HY-19231Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-19231Size:1 Each
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Description
DPI-3290 (Org 41793) is a potent and specific opioid receptors agonist with Ki values of 0.18 nM, 0.46 nM, and 0.62 nM for δ-, μ-, and κ-opioid receptors, respectively. DPI-3290 is one of a series of novel centrally acting agents with potent antinociceptive activity[1].
CAS Number
[182417-73-8]
Product Name Alternative
Org 41793
UNSPSC
12352005
Target
Opioid Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/dpi-3290.html
Solubility
10 mM in DMSO
Smiles
O=C(N(C1=CC=CC(F)=C1)C)C2=CC=CC([C@@H](N3[C@@H](C)CN(CC=C)[C@H](C)C3)C4=CC=CC(O)=C4)=C2
Molecular Formula
C30H34FN3O2
Molecular Weight
487.61
References & Citations
[1]Gengo PJ, et al. DPI-3290 [ (+) -3- ((alpha-R) -alpha- ((2S,5R) -4-allyl-2,5-dimethyl-1-piperazinyl) -3-hydroxybenzyl) -N- (3-fluorophenyl) -N-methylbenzamide]. I. A mixed opioid agonist with potent antinociceptive activity. J Pharmacol Exp Ther. 2003 Dec;307 (3) :1221-6.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 2
Isoform
δ Opioid Receptor/DOR; κ Opioid Receptor/KOR

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