DPI-3290

• Description:

  DPI-3290 (Org 41793) is a potent and specific opioid receptors agonist with Ki values of 0.18 nM, 0.46 nM, and 0.62 nM for δ-, μ-, and κ-opioid receptors, respectively. DPI-3290 is one of a series of novel centrally acting agents with potent antinociceptive activity[1].

• Product Name Alternative:

  Org 41793

• UNSPSC:

  12352005

• Target:

  Opioid Receptor

• Type:

  Reference compound

• Related Pathways:

  GPCR/G Protein; Neuronal Signaling

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/dpi-3290.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C (N (C1=CC=CC (F) =C1) C) C2=CC=CC ([C@@H] (N3[C@@H] (C) CN (CC=C) [C@H] (C) C3) C4=CC=CC (O) =C4) =C2

• Molecular Formula:

  C30H34FN3O2

• Molecular Weight:

  487.61

• References & Citations:

  [1]Gengo PJ, et al. DPI-3290 [ (+) -3- ((alpha-R) -alpha- ((2S,5R) -4-allyl-2,5-dimethyl-1-piperazinyl) -3-hydroxybenzyl) -N- (3-fluorophenyl) -N-methylbenzamide]. I. A mixed opioid agonist with potent antinociceptive activity. J Pharmacol Exp Ther. 2003 Dec;307 (3) :1221-6.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  Phase 2

• Isoform:

  δ Opioid Receptor/DOR; κ Opioid Receptor/KOR

• CAS Number:

  182417-73-8