DPI-3290

• UNSPSC Description:

  DPI-3290 (Org 41793) is a potent and specific opioid receptors agonist with Ki values of 0.18 nM, 0.46 nM, and 0.62 nM for δ-, μ-, and κ-opioid receptors, respectively. DPI-3290 is one of a series of novel centrally acting agents with potent antinociceptive activity[1].

• Target Antigen:

  Opioid Receptor

• Type:

  Reference compound

• Related Pathways:

  GPCR/G Protein;Neuronal Signaling

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/dpi-3290.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C(N(C1=CC=CC(F)=C1)C)C2=CC=CC([C@@H](N3[C@@H](C)CN(CC=C)[C@H](C)C3)C4=CC=CC(O)=C4)=C2

• Molecular Weight:

  487.61

• References & Citations:

  [1]Gengo PJ, et al. DPI-3290 [(+)-3-((alpha-R)-alpha-((2S,5R)-4-allyl-2,5-dimethyl-1-piperazinyl)-3-hydroxybenzyl)-N-(3-fluorophenyl)-N-methylbenzamide]. I. A mixed opioid agonist with potent antinociceptive activity. J Pharmacol Exp Ther. 2003 Dec;307(3):1221-6.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  Phase 2

• CAS Number:

  182417-73-8