DPI-3290

• Description :

  DPI-3290 (Org 41793) is a potent and specific opioid receptors agonist with Ki values of 0.18 nM, 0.46 nM, and 0.62 nM for δ-, μ-, and κ-opioid receptors, respectively. DPI-3290 is one of a series of novel centrally acting agents with potent antinociceptive activity[1].

• Product Name Alternative :

  Org 41793

• UNSPSC :

  12352005

• Target :

  Opioid Receptor

• Type :

  Reference compound

• Related Pathways :

  GPCR/G Protein; Neuronal Signaling

• Applications :

  Neuroscience-Neuromodulation

• Field of Research :

  Neurological Disease

• Assay Protocol :

  https://www.medchemexpress.com/dpi-3290.html

• Solubility :

  10 mM in DMSO

• Smiles :

  O=C(N(C1=CC=CC(F)=C1)C)C2=CC=CC([C@@H](N3[C@@H](C)CN(CC=C)[C@H](C)C3)C4=CC=CC(O)=C4)=C2

• Molecular Formula :

  C30H34FN3O2

• Molecular Weight :

  487.61

• References & Citations :

  [1]Gengo PJ, et al. DPI-3290 [ (+) -3- ((alpha-R) -alpha- ((2S,5R) -4-allyl-2,5-dimethyl-1-piperazinyl) -3-hydroxybenzyl) -N- (3-fluorophenyl) -N-methylbenzamide]. I. A mixed opioid agonist with potent antinociceptive activity. J Pharmacol Exp Ther. 2003 Dec;307 (3) :1221-6.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  Phase 2

• Isoform :

  δ Opioid Receptor/DOR; κ Opioid Receptor/KOR

• CAS Number :

  [182417-73-8]