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DPI 201-106 (Standard)

CAT: 0804-HY-19666RSize: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-19666RSize:1 Each
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Description
DPI 201-106 (Standard) is the analytical standard of DPI 201-106. This product is intended for research and analytical applications. DPI 201-106 (SDZ 201106) is a cardiotonic agent with a synergistic sarcolemmal and intracellular mechanism of action. DPI 201-106 shows cardioselective modulation of voltage-gated sodium channels (VGSCs) resulting in a positive inotropic effect[1][2][3].
CAS Number
97730-95-5
UNSPSC
12352100
Target
Reference Standards; Sodium Channel
Related Pathways
Membrane Transporter/Ion Channel; Others
Field of Research
Cardiovascular Disease
Smiles
N#CC(N1)=CC2=C1C=CC=C2OCC(O)CN3CCN(C(C4=CC=CC=C4)C5=CC=CC=C5)CC3
Molecular Formula
C29H30N4O2
Molecular Weight
466.57
References & Citations
[1]G Scholtysik, et al. DPI 201-106, a novel cardioactive agent. Combination of cAMP-independent positive inotropic, negative chronotropic, action potential prolonging and coronary dilatory properties. Naunyn Schmiedebergs Arch Pharmacol.1985 May;329 (3) :316-25.|[2]G Scholtysik, et al. Interaction of DPI 201-106 with cardiac glycosides. J Cardiovasc Pharmacol. 1989 Feb;13 (2) :342-7.|[3]M Mevissen, et al. Identification of a cardiac sodium channel insensitive to synthetic modulators. J Cardiovasc Pharmacol Ther. 2001 Apr;6 (2) :201-12.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards

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