Ro 41-3290

• UNSPSC Description:

  Ro 41-3290 is the desethylated derivative of Ro 41-3696, which is a nonbenzodiazepine partial agonist at the benzodiazepine receptor.

• Target Antigen:

  GABA Receptor

• Type:

  Reference compound

• Related Pathways:

  Membrane Transporter/Ion Channel;Neuronal Signaling

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/Ro_41-​3290.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O[C@@H]1CN(C(C2=C3N(C(C(C4=CC=CC=C4)=C2)=O)CCC5=CC=C(Cl)C=C53)=O)CC1

• Molecular Weight:

  420.89

• References & Citations:

  [1]Dingemanse J, et al. Pharmacokinetics and pharmacodynamics of Ro 41-3696, a novel nonbenzodiazepine hypnotic. J Clin Pharmacol. 1995 Aug;35(8):821-9.|[2]Dingemanse J, et al. Multiple-dose tolerability, pharmacodynamics, and pharmacokinetics of the quinolizinone hypnotic Ro 41-3696 in elderly subjects. Clin Neuropharmacol. 2001 Mar-Apr;24(2):82-90.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  143943-72-0