Ro 41-3290

• Description :

  Ro 41-3290 is the desethylated derivative of Ro 41-3696, which is a nonbenzodiazepine partial agonist at the benzodiazepine receptor.

• UNSPSC :

  12352005

• Target :

  GABA Receptor

• Type :

  Reference compound

• Related Pathways :

  Membrane Transporter/Ion Channel; Neuronal Signaling

• Applications :

  Neuroscience-Neuromodulation

• Field of Research :

  Neurological Disease

• Assay Protocol :

  https://www.medchemexpress.com/Ro_41-​3290.html

• Solubility :

  10 mM in DMSO

• Smiles :

  O[C@@H]1CN(C(C2=C3N(C(C(C4=CC=CC=C4)=C2)=O)CCC5=CC=C(Cl)C=C53)=O)CC1

• Molecular Formula :

  C24H21ClN2O3

• Molecular Weight :

  420.89

• References & Citations :

  [1]Dingemanse J, et al. Pharmacokinetics and pharmacodynamics of Ro 41-3696, a novel nonbenzodiazepine hypnotic. J Clin Pharmacol. 1995 Aug;35 (8) :821-9.|[2]Dingemanse J, et al. Multiple-dose tolerability, pharmacodynamics, and pharmacokinetics of the quinolizinone hypnotic Ro 41-3696 in elderly subjects. Clin Neuropharmacol. 2001 Mar-Apr;24 (2) :82-90.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [143943-72-0]