Ko-3290

• Description:

  Ko-3290 is an antagonist of β-adrenoceptor, with cardioselectivity and antilipolytic effects in animals. Ko-3290 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

• UNSPSC:

  12352005

• Target:

  Adrenergic Receptor

• Type:

  Reference compound

• Related Pathways:

  GPCR/G Protein; Neuronal Signaling

• Applications:

  Metabolism-protein/nucleotide metabolism

• Field of Research:

  Cardiovascular Disease; Endocrinology

• Assay Protocol:

  https://www.medchemexpress.com/Ko-3290.html

• Solubility:

  10 mM in DMSO

• Smiles:

  CC (C) C (NC1=CC=C (OCC (O) CNC (C) (C) C#C) C (C#N) =C1) =O

• Molecular Formula:

  C19H25N3O3

• Molecular Weight:

  343.42

• References & Citations:

  [1]T.H.PRINGLE, et al. The assessment of the-3-adrenoceptor blocking activity and cardioselectivity of Koe3290 innormal subjects. British Journal of Clinical Pharmacology (1987), 24 (5), 581-9

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• Isoform:

  β adrenergic receptor

• CAS Number:

  79848-61-6