Ko-3290

• Description :

  Ko-3290 is an antagonist of β-adrenoceptor, with cardioselectivity and antilipolytic effects in animals. Ko-3290 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

• UNSPSC :

  12352005

• Target :

  Adrenergic Receptor

• Type :

  Reference compound

• Related Pathways :

  GPCR/G Protein; Neuronal Signaling

• Applications :

  Metabolism-protein/nucleotide metabolism

• Field of Research :

  Cardiovascular Disease; Endocrinology

• Assay Protocol :

  https://www.medchemexpress.com/Ko-3290.html

• Solubility :

  10 mM in DMSO

• Smiles :

  CC(C)C(NC1=CC=C(OCC(O)CNC(C)(C)C#C)C(C#N)=C1)=O

• Molecular Formula :

  C19H25N3O3

• Molecular Weight :

  343.42

• References & Citations :

  [1]T.H.PRINGLE, et al. The assessment of the-3-adrenoceptor blocking activity and cardioselectivity of Koe3290 innormal subjects. British Journal of Clinical Pharmacology (1987), 24 (5), 581-9

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• Isoform :

  β adrenergic receptor

• CAS Number :

  [79848-61-6]