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BMS-767778

CAT: 0804-HY-16656Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-16656Size:1 Each
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Description
BMS-767778 is a selective DPP4 inhibitor, with a Ki of 0.9 nM[1].
CAS Number
915729-95-2
UNSPSC
12352005
Target
Dipeptidyl Peptidase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/bms-767778.html
Solubility
10 mM in DMSO
Smiles
O=C(N(C)C)CN1CC2=NC(C)=C(CN)[C@]([C@]3=CC=C(Cl)C=C3Cl)=C2C1=O
Molecular Formula
C19H20Cl2N4O2
Molecular Weight
407.29
References & Citations
[1]Pratik Devasthale, et al. Optimization of activity, selectivity, and liability profiles in 5-oxopyrrolopyridine DPP4 inhibitors leading to clinical candidate (Sa) -2- (3- (aminomethyl) -4- (2,4-dichlorophenyl) -2-methyl-5-oxo-5H-pyrrolo[3,4-b]pyridin-6 (7H) -yl) -N, N-dimethylacetamide (BMS-767778) . J Med Chem . 2013 Sep 26;56 (18) :7343-57.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 1

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