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AlF-PD-FAPI

CAT: 0804-HY-163079Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-163079Size:1 Each
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Description
AlF-PD-FAPI has affinity for FAP , with the IC50 of 0.13 nM, and shows a specific uptake, high internalized fraction, and low cellular efflux in vitro. AlF-PD-FAPI can be used as FAP-targeting tracer[1].
UNSPSC
12352005
Target
FAP
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/alf-pd-fapi.html
Solubility
10 mM in DMSO
Smiles
[H][C@]1(CC(F)(CN1C(CNC(C2=CC=NC3=CC=C(C=C32)OCCOCCOCCNC([C@@H](NC(CN4CCN(CCN(CC4)C5)CC(O[Al](F)OC5=O)=O)=O)CC(N[C@H](C(O)=O)CC(O)=O)=O)=O)=O)=O)F)C#N
Molecular Formula
C43H54AlF3N10O16
Molecular Weight
1050.92
References & Citations
[1]Hui Zhou, et al. Synthesis and preclinical evaluation of novel 18F-labeled fibroblast activation protein tracers for positron emission tomography imaging of cancer-associated fibroblasts. European Journal of Medicinal Chemistry Volume 264, 15 January 2024, 115993
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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