FAPI-mFS

CAT: 0804-HY-164725-01Size: 1 mgDry Ice: NoHazardous: No
CAT#:0804-HY-164725-01Size:1 mg
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Description
FAPI-mFS is an irreversible fibroblast activation protein (FAP) inhibitor, that enhances the uptake and retention time in cancer cells through its covalent binding property for FAP. FAPI-mFS can be used for cancer imaging the therapy, when labeled with radioactive 68Ga or 177Lu[1]. FAPI-mFS can be used for the synthesis/research of Radionuclide-Drug Conjugates (RDCs) .
CAS Number
[3023869-94-2]
UNSPSC
12352209
Target
FAP; Radionuclide-Drug Conjugates (RDCs)
Type
Peptides
Related Pathways
Antibody-drug Conjugate/ADC Related; Immunology/Inflammation
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/fapi-mfs.html
Purity
99.78
Solubility
DMSO : ≥ 100 mg/mL
Smiles
O=C(N[C@H](C(N1CCN(CCCOC2=CC=C(N=CC=C3C(NCC(N4[C@H](C#N)CC(F)(F)C4)=O)=O)C3=C2)CC1)=O)CCCCNC(C5=CC(OS(F)(=O)=O)=CC=C5)=O)CN6CCN(CC(O)=O)CCN(CC(O)=O)CCN(CC(O)=O)CC6
Molecular Formula
C53H69F3N12O15S
Molecular Weight
1203.25
References & Citations
[1]Cui XY, et al., Covalent targeted radioligands potentiate radionuclide therapy. Nature. 2024 Jun;630 (8015) :206-213.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
Scientific Category
Peptides
Clinical Information
No Development Reported

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