FAPI-P8PN

• Description :

  FAPI-P8PN is a fibroblast activation protein (FAP) inhibitor (IC50=3.6 nM) . FAPI-P8PN is promising for research of FAP-overexpressing solid tumors[1].

• UNSPSC :

  12352005

• Target :

  FAP

• Related Pathways :

  Immunology/Inflammation

• Field of Research :

  Cancer

• Smiles :

  [O-]P(OCC(NCCCC[C@@H](C(NCCOCCOCCOCCOCCOCCOCCOCCOCCC(NC1=C2N=CC=C(C2=CC=C1)C(NCC(N3CC(F)(C[C@H]3C#N)F)=O)=O)=O)=O)NC(CN4CCN(CCN(CCN(CC4)CC(O)=O)CC(O)=O)CC(O)=O)=O)=O)(OCC[N+](C)(C)C)=O

• Molecular Formula :

  C65H104F2N13O24P

• Molecular Weight :

  1520.56

• References & Citations :

  [1]Yuan H, et al. Structural Optimization of Fibroblast Activation Protein Inhibitors Through Zwitterionic and PEG Modification Strategy: Impact on Pharmacokinetics and Tumor Imaging. Mol Pharm. 2025 Aug 4;22 (8) :4831-4843.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [2921619-09-0]