Antimalarial agent 35

• Description:

  Antimalarial agent 35 (compound QP11) is a selective inhibitor FP2. Antimalarial agent 35 has antimalarial activity and shows synergistic effects when combined with chloroquine (HY-17589A) [1].

• UNSPSC:

  12352005

• Target:

  Parasite

• Type:

  Reference compound

• Related Pathways:

  Anti-infection

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Infection

• Assay Protocol:

  https://www.medchemexpress.com/antimalarial-agent-35.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=[N+](C1=CC(NC(CN2C=C(N=N2)CN3CCN(CC3)C4=CC=NC5=CC(Cl)=CC=C45)=O)=CC=C1)[O-]

• Molecular Formula:

  C24H23ClN8O3

• Molecular Weight:

  506.94

• References & Citations:

  [1]Amad Uddin, et al. Blood-stage antimalarial activity, favourable metabolic stability and in vivo toxicity of novel piperazine linked 7-chloroquinoline-triazole conjugates. Eur J Med Chem. 2023.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  [3054155-49-3]