Antimalarial agent 34

Antimalarial agent 34

• CAS Number: 9007-83-4
• UNSPSC Description: Antimalarial agent 34 is a modest PfARK1/3 inhibitor and shows potent antiplasmodial activity (EC50 = 0.16 μM)[1].
• Target Antigen: Parasite
• Type: Reference compound
• Related Pathways: Anti-infection
• Applications: COVID-19-immunoregulation
• Field of Research: Infection
• Assay Protocol: https://www.medchemexpress.com/antimalarial-agent-34.html
• Solubility: 10 mM in DMSO
• Smiles: CS(=O)(NC1=CC=CC=C1NC2=NC(NC3=CC=C(N4CCOCC4)C(OC)=C3)=NC=C2Cl)=O
• Molecular Weight: 504.99
• References & Citations: [1]Han Wee Ong, et al. Characterization of 2,4-Dianilinopyrimidines Against Five P. falciparum Kinases PfARK1, PfARK3, PfNEK3, PfPK9, and PfPKB. ACS Med Chem Lett. 2023 Nov 27;14(12):1774-1784.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported