MSA-2-Pt

• Description :

  MSA-2-Pt is an orally active STING agonist that has good cell membrane permeability. MSA-2-Pt can induce cell death by Pt, which may release damaged DNA to activate the cGAS-STING pathway. Besides, MSA-2-Pt can activate the STING pathway directly by MSA-2. MSA-2-Pt can be used for the research of cancer[1].

• UNSPSC :

  12352211

• Target :

  STING

• Type :

  Reference compound

• Related Pathways :

  Immunology/Inflammation

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/msa-2-pt.html

• Solubility :

  10 mM in DMSO

• Smiles :

  O=C(CCC(O[Pt]([NH3])(OC(CCC(C1=CC2=CC(OC)=C(OC)C=C2S1)=O)=O)[NH3])=O)C3=CC4=CC(OC)=C(OC)C=C4S3

• Molecular Formula :

  C28H32N2O10PtS2

• Molecular Weight :

  815.78

• References & Citations :

  [1]Wang M, et al. Antitumor Effect of Platinum-Modified STING Agonist MSA-2[J]. ACS Omega, 2024.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported