PT-ttpy
CAT:
804-HY-W543137
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
PT-ttpy
- CAS Number: 727721-37-1
- UNSPSC Description: Pt-ttpy, a metallo-organic complex and potent G-quadruplex ligand, effectively triggers substantial telomere-related DNA damage in cancer cells by inhibiting telomerase and/or telomere functions, while also causing various chromatin abnormalities during mitosis, such as chromatin bridges, ultrafine bridges (UFBs), and double-stranded breaks (DSBs).
- Target Antigen: DNA/RNA Synthesis; G-quadruplex
- Type: Reference compound
- Related Pathways: Cell Cycle/DNA Damage
- Applications: Cancer-programmed cell death
- Field of Research: cancer
- Assay Protocol: https://www.medchemexpress.com/pt-ttpy.html
- Smiles: [Cl-][Pt+2]12[N]3=C(C4=CC(C5=CC=C(C)C=C5)=CC(C6=[N]2C=CC=C6)=[N]41)C=CC=C3.[Cl-]
- Molecular Weight: 589.38
- References & Citations: [1]P.P. Losada et al.Fresenius Journal of Analytical Chemistry1993
- Shipping Conditions: Room temperature
- Clinical Information: No Development Reported