MSA-2 dimer

• UNSPSC Description:

  MSA-2 dimer is a selective, orally active non-nucleotide STING agonist (Kd=145 μM) with long-term antitumor and immunogenic activity. MSA-2 dimer is bound to STING as a non-covalent dimer exhibiting higher permeability than cyclic dinucleotide[1].

• Target Antigen:

  STING

• Type:

  Reference compound

• Related Pathways:

  Immunology/Inflammation

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Cancer; Inflammation/Immunology

• Assay Protocol:

  https://www.medchemexpress.com/msa-2-dimer.html

• Solubility:

  DMSO : 70 mg/mL (ultrasonic)

• Smiles:

  O=C(CCC(C1=CC2=C(C=C(C(CCCC3=CC4=C(C=C3OC)SC(C(CCC(O)=O)=O)=C4)=C2)OC)S1)=O)O

• Molecular Weight:

  568.66

• References & Citations:

  [1]Pan BS, et al. An orally available non-nucleotide STING agonist with antitumor activity. Science. 2020;369(6506):eaba6098.

• Shipping Conditions:

  Room Temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  2377881-92-8