PT-91

• Description:

  PT-91 is an agonist of GPR27. PT-91 exhibits high metabolic stability and brain exposure in mice[1].

• UNSPSC:

  12352005

• Target:

  Orphan GPCR; Orphan Receptor

• Type:

  Reference compound

• Related Pathways:

  GPCR/G Protein

• Applications:

  Metabolism-protein/nucleotide metabolism

• Field of Research:

  Metabolic Disease; Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/pt-91.html

• Concentration:

  10mM

• Purity:

  98.25

• Solubility:

  DMSO : ≥ 100 mg/mL

• Smiles:

  O=C(C1=CC=C(C=C1OC)C(F)(F)F)NC2=CC=C(C=C2)S(NC3=CC=CC=C3)(=O)=O

• Molecular Formula:

  C21H17F3N2O4S

• Molecular Weight:

  450.43

• References & Citations:

  [1]Pillaiyar T, et al. Development of Ligands for the Super Conserved Orphan G Protein-Coupled Receptor GPR27 with Improved Efficacy and Potency. J Med Chem. 2023 Dec 7.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  [3037561-48-8]