ZIKV-IN-8

• Description:

  ZIKV-IN-8 (Compound 9b) is a noncompetitive Zika virus (ZIKV) inhibitor. ZIKV-IN-8 shows the best anti-ZIKV activity with a selectivity index of 22.4. ZIKV-IN-8 has significant inhibition of ZIKV with an IC50 value of 25.6 μM. ZIKV-IN-8 can be used for the research of ZIKV infection[1].

• UNSPSC:

  12352005

• Target:

  Influenza Virus

• Type:

  Reference compound

• Related Pathways:

  Anti-infection

• Applications:

  COVID-19-anti-virus

• Field of Research:

  Infection

• Assay Protocol:

  https://www.medchemexpress.com/zikv-in-8.html

• Solubility:

  10 mM in DMSO

• Smiles:

  CC1=C(C(C2=O)=NN1C3=CC=C(OC)C=C3)C(C)=NN2CC4=CC([N+]([O-])=O)=CC=C4

• Molecular Formula:

  C21H19N5O4

• Molecular Weight:

  405.41

• References & Citations:

  [1]Quang De Tran, et al. ZIKV Inhibitors Based on Pyrazolo[3,4-d]pyridazine-7-one Core: Rational Design, In Vitro Evaluation, and Theoretical Studies. ACS Omega 2023 8 (51), 48994-49008

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  [3022924-04-2]