ZIKV-IN-8

• Description :

  ZIKV-IN-8 (Compound 9b) is a noncompetitive Zika virus (ZIKV) inhibitor. ZIKV-IN-8 shows the best anti-ZIKV activity with a selectivity index of 22.4. ZIKV-IN-8 has significant inhibition of ZIKV with an IC50 value of 25.6 μM. ZIKV-IN-8 can be used for the research of ZIKV infection[1].

• UNSPSC :

  12352005

• Target :

  Influenza Virus

• Type :

  Reference compound

• Related Pathways :

  Anti-infection

• Applications :

  COVID-19-anti-virus

• Field of Research :

  Infection

• Assay Protocol :

  https://www.medchemexpress.com/zikv-in-8.html

• Solubility :

  10 mM in DMSO

• Smiles :

  CC1=C(C(C2=O)=NN1C3=CC=C(OC)C=C3)C(C)=NN2CC4=CC([N+]([O-])=O)=CC=C4

• Molecular Formula :

  C21H19N5O4

• Molecular Weight :

  405.41

• References & Citations :

  [1]Quang De Tran, et al. ZIKV Inhibitors Based on Pyrazolo[3,4-d]pyridazine-7-one Core: Rational Design, In Vitro Evaluation, and Theoretical Studies. ACS Omega 2023 8 (51), 48994-49008

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [3022924-04-2]