Products for Research Use Only
RegisterLogin

ZIKV-IN-3

CAT: 0804-HY-151446Size: 1 EachDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-151446Size:1 Each
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
ZIKV-IN-3 (compound 5a), an andrographolide derivatives, is a potent ZIKV NS5 methyl transferase (MTase) inhibitor with an IC50 value of 18.34 μM. ZIKV-IN-3 inhibits ZIKV replication and infection. ZIKV-IN-3 can be used in research of Zika virus (ZIKV) [1].
CAS Number
947699-46-9
UNSPSC
12352005
Target
DNA Methyltransferase; Flavivirus; Virus Protease
Type
Reference compound
Related Pathways
Anti-infection; Epigenetics
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/zikv-in-3.html
Solubility
10 mM in DMSO
Smiles
O=C1OCC=C1/C=C/[C@@H]2C(CC[C@]3([H])[C@@](COC(C4=CC=CC=C4)(C5=CC=CC=C5)C6=CC=CC=C6)(C)/C(CC[C@@]23C)=N/O)=C
Molecular Formula
C39H41NO4
Molecular Weight
587.75
References & Citations
[1]Qian W, et al. Discovery of dehydroandrographolide derivatives with C19 hindered ether as potent anti-ZIKV agents with inhibitory activities to MTase of ZIKV NS5. Eur J Med Chem. 2022 Aug 27;243:114710.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Related Products

CatalogName
HY-151448ZIKV-IN-5
HY-151447ZIKV-IN-4
HY-146957ZIKV-IN-1
HY-155053ZIKV-IN-6
HY-162073ZIKV-IN-8
HY-151445ZIKV-IN-2
HY-161642DENV-2/ZIKV-IN-1
HY-146193Zika virus-IN-3
HY-W081226-013,3,3-Trifluoropropionyl chloride
HY-W127810-013,3',3''-Nitrilotripropionic Acid

Alternative Products

CatalogName
T73292-01ZIKV-IN-3
P521865ZIKV-NS1 Protein (N-His, ZIKV)
P529618ZIKV-NS1 Protein (C-His, ZIKV)
P529614ZIKV-E Protein (C-His, ZIKV)
P529619ZIKV-NS5 Protein (C-His, ZIKV)
533751ZIKV-IN-K22
T80729-01ZIKV-IN-6
T63131-01ZIKV-IN-1
MBS5806201ZIKV-IN-4
MBS5806731ZIKV-IN-2

Popular Products