ZIKV-IN-6

• Target:

  Others|||Anti-infection|||DNA/RNA Synthesis

• Related Pathways:

  Others|||Cell Cycle/Checkpoint|||Microbiology/Virology|||DNA Damage/DNA Repair

• Bioactivity:

  ZIKV-IN-6 (compound 22) is a direct inhibitor of the Zika virus (ZIKV) that binds to its RNA-dependent RNA polymerase (RdRp), obstructing viral RNA synthesis mediated by the ZIKV NS5 protein. The compound exhibits low cytotoxicity (CC50 >50 ?M) and mitigates excessive inflammatory response and pyroptosis [1].

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C