Products for Research Use Only

ZIKV-IN-6

CAT: 0931-T80729-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0931-T80729-01Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Target
Others, Anti-infection, DNA/RNA Synthesis
Related Pathways
Others, Cell Cycle/Checkpoint, Microbiology/Virology, DNA Damage/DNA Repair
Bioactivity
ZIKV-IN-6 (compound 22) is a direct inhibitor of the Zika virus (ZIKV) that binds to its RNA-dependent RNA polymerase (RdRp), obstructing viral RNA synthesis mediated by the ZIKV NS5 protein. The compound exhibits low cytotoxicity (CC50 >50 μM) and mitigates excessive inflammatory response and pyroptosis [1].
Shipping Conditions
Ice Packs
Storage Temperature
-20°C