ZIKV-IN-5

CAT: 0804-HY-151448Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-151448Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
ZIKV-IN-5 (compound 5c) is a low-cytotoxicity and acid-stable anti-ZIKV agent (EC50=0.71 μM) . ZIKV-IN-5 effectively inhibits the activity of ZIKV NS5 MTase[1].
UNSPSC
12352005
Target
Virus Protease
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/zikv-in-5.html
Solubility
10 mM in DMSO
Smiles
O=C1OCC=C1/C=C/[C@@H]2C(CC[C@]3([H])[C@](C)(CO[Si](C4=CC=CC=C4)(C(C)(C)C)C5=CC=CC=C5)/C(CC[C@@]23C)=N/O)=C
Molecular Formula
C36H45NO4Si
Molecular Weight
583.83
References & Citations
[1]Qian W, et al. Discovery of dehydroandrographolide derivatives with C19 hindered ether as potent anti-ZIKV agents with inhibitory activities to MTase of ZIKV NS5. Eur J Med Chem. 2022 Aug 27;243:114710.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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