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ZIKV-IN-2

CAT: 0804-HY-151445Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-151445Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
ZIKV-IN-2 (compound 3a) is a potent ZIKV NS5 methyl transferase (MTase) inhibitor with an IC50 value of 38.86 μM. ZIKV-IN-2 inhibits ZIKV replication and infection. ZIKV-IN-2 can be used in research of Zika virus (ZIKV) [1].
CAS Number
910582-16-0
UNSPSC
12352005
Target
DNA Methyltransferase; Flavivirus; Virus Protease
Type
Reference compound
Related Pathways
Anti-infection; Epigenetics
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/zikv-in-2.html
Solubility
10 mM in DMSO
Smiles
[H][C@]12CCC([C@H]([C@@]1(CC[C@H]([C@]2(COC(C3=CC=CC=C3)(C4=CC=CC=C4)C5=CC=CC=C5)C)O)C)/C=C/C6=CCOC6=O)=C
Molecular Formula
C39H42O4
Molecular Weight
574.75
References & Citations
[1]Qian W, et al. Discovery of dehydroandrographolide derivatives with C19 hindered ether as potent anti-ZIKV agents with inhibitory activities to MTase of ZIKV NS5. Eur J Med Chem. 2022 Aug 27;243:114710.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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