ZIKV-IN-2

ZIKV-IN-2

• CAS Number: 910582-16-0
• UNSPSC Description: ZIKV-IN-2 (compound 3a) is a potent ZIKV NS5 methyl transferase (MTase) inhibitor with an IC50 value of 38.86 μM. ZIKV-IN-2 inhibits ZIKV replication and infection. ZIKV-IN-2 can be used in research of Zika virus (ZIKV)[1].
• Target Antigen: DNA Methyltransferase; Flavivirus; Virus Protease
• Type: Reference compound
• Related Pathways: Anti-infection;Epigenetics
• Applications: COVID-19-anti-virus
• Field of Research: Infection
• Assay Protocol: https://www.medchemexpress.com/zikv-in-2.html
• Solubility: 10 mM in DMSO
• Smiles: [H][C@]12CCC([C@H]([C@@]1(CC[C@H]([C@]2(COC(C3=CC=CC=C3)(C4=CC=CC=C4)C5=CC=CC=C5)C)O)C)/C=C/C6=CCOC6=O)=C
• Molecular Weight: 574.75
• References & Citations: [1]Qian W, et al. Discovery of dehydroandrographolide derivatives with C19 hindered ether as potent anti-ZIKV agents with inhibitory activities to MTase of ZIKV NS5. Eur J Med Chem. 2022 Aug 27;243:114710.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported