ZIKV-IN-2

• UNSPSC Description:

  ZIKV-IN-2 (compound 3a) is a potent ZIKV NS5 methyl transferase (MTase) inhibitor with an IC50 value of 38.86 μM. ZIKV-IN-2 inhibits ZIKV replication and infection. ZIKV-IN-2 can be used in research of Zika virus (ZIKV)[1].

• Target Antigen:

  DNA Methyltransferase; Flavivirus; Virus Protease

• Type:

  Reference compound

• Related Pathways:

  Anti-infection;Epigenetics

• Applications:

  COVID-19-anti-virus

• Field of Research:

  Infection

• Assay Protocol:

  https://www.medchemexpress.com/zikv-in-2.html

• Solubility:

  10 mM in DMSO

• Smiles:

  [H][C@]12CCC([C@H]([C@@]1(CC[C@H]([C@]2(COC(C3=CC=CC=C3)(C4=CC=CC=C4)C5=CC=CC=C5)C)O)C)/C=C/C6=CCOC6=O)=C

• Molecular Weight:

  574.75

• References & Citations:

  [1]Qian W, et al. Discovery of dehydroandrographolide derivatives with C19 hindered ether as potent anti-ZIKV agents with inhibitory activities to MTase of ZIKV NS5. Eur J Med Chem. 2022 Aug 27;243:114710.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  910582-16-0