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ZIKV-IN-4

CAT: 0804-HY-151447Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-151447Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
ZIKV-IN-4 (compound 5b) is a low-cytotoxicity and acid-stable anti-ZIKV agent (EC50=3.49 μM) . ZIKV-IN-4 effectively inhibits the activity of ZIKV NS5 MTase[1].
UNSPSC
12352005
Target
Virus Protease
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/zikv-in-4.html
Solubility
10 mM in DMSO
Smiles
C=C(CC[C@]1([H])[C@@]/2(COC(C3=CC=CC=C3)C4=CC=CC=C4)C)[C@@H](/C=C/C5=CCOC5=O)[C@]1(C)CCC2=N/O
Molecular Formula
C33H37NO4
Molecular Weight
511.65
References & Citations
[1]Qian W, et al. Discovery of dehydroandrographolide derivatives with C19 hindered ether as potent anti-ZIKV agents with inhibitory activities to MTase of ZIKV NS5. Eur J Med Chem. 2022 Aug 27;243:114710.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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