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Antimalarial agent 36

CAT: 0804-HY-161170Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-161170Size:1 Each
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Description
Antimalarial agent 36 (compound 1) is an antimalarial agent, with the EC50s of 58 nM and 42 nM, for Dd2 and 3D7, respectively. Antimalarial agent 36 targets EphA2[1].
CAS Number
2982633-03-2
UNSPSC
12352005
Target
Parasite
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/antimalarial-agent-36.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=CC(C2=CC=CS2)=CN=C1)NC3=CC(Cl)=CC(C(NC4=CC=C(C(C(F)(F)F)=C4)CN5CCN(CC5)CC)=O)=C3
Molecular Formula
C31H29ClF3N5O2S
Molecular Weight
628.11
References & Citations
[1]Wang L, et al. Discovery of Potent Antimalarial Type II Kinase Inhibitors with Selectivity over Human Kinases. J Med Chem. 2024 Jan 25;67 (2) :1460-1480.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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