AChE-IN-49

• Description :

  AChE-IN-49 (Compd (S) -7g) is an acetylcholinesterase (AChE) inhibitor, with an IC50 of 0.0003 μM[1].

• UNSPSC :

  12352005

• Target :

  Cholinesterase (ChE)

• Type :

  Reference compound

• Related Pathways :

  Neuronal Signaling

• Applications :

  Metabolism-protein/nucleotide metabolism

• Field of Research :

  Metabolic Disease

• Assay Protocol :

  https://www.medchemexpress.com/ache-in-49.html

• Solubility :

  10 mM in DMSO

• Smiles :

  COC1=C(OC)C(C2=CC=CC=C2C3)=C([C@@]3([H])N(C(C4=CC=[N+](CC5=CC=CC=C5Cl)C=C4)=O)CC6)C6=C1.[Br-]

• Molecular Formula :

  C31H28BrClN2O3

• Molecular Weight :

  591.92

• References & Citations :

  [1]Aya M Soliman, et al. Piperazine-2-carboxylic acid derivatives as MTDLs anti-Alzheimer agents: Anticholinesterase activity, mechanistic aspect, and molecular modeling studies. Bioorg Chem. 2024 Jan:142:106916.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported