AChE-IN-7

CAT: 0804-HY-144660Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-144660Size:1 Each
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Description
AChE-IN-7 (Compound 16) is a selective and potent inhibitor of acetylcholinesterase (eeAChE IC50 = 0.045 μM; eeBuChE IC50 = 19.68 μM) . AChE-IN-7 is safe in vivo and in vitro, and shows good overall pharmacokinetic performance and high bioavailability (F = 55.5%) . AChE-IN-7 also has high BBB permeability[1].
CAS Number
[2699090-78-1]
UNSPSC
12352005
Target
Cholinesterase (ChE)
Type
Reference compound
Related Pathways
Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/ache-in-7.html
Solubility
10 mM in DMSO
Smiles
O=C1C2=C(C3=NC=CC4=CC(OCCCCN5CCCCC5C)=CC1=C43)C=CC=C2
Molecular Formula
C26H28N2O2
Molecular Weight
400.51
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
AChE

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