AChE-IN-8

• Description:

  AChE-IN-8 (Compound 19) is a potent inhibitor of AChE with an IC50 of 1.95 μM. AChE-IN-8 has the potential for the research of Alzheimer's disease[1].

• UNSPSC:

  12352005

• Target:

  Cholinesterase (ChE)

• Type:

  Reference compound

• Related Pathways:

  Neuronal Signaling

• Applications:

  Neuroscience-Neurodegeneration

• Field of Research:

  Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/ache-in-8.html

• Solubility:

  10 mM in DMSO

• Smiles:

  CCNC(N/N=C/C1=C2NC=C(C2=C(C=C1OC)OC)C3=CC=CC=C3)=S

• Molecular Formula:

  C20H22N4O2S

• Molecular Weight:

  382.48

• References & Citations:

  [1]Yıldız M, et al. Dimethoxyindoles based thiosemicarbazones as multi-target agents; synthesis, crystal interactions, biological activity and molecular modeling [published online ahead of print, 2022 Jan 30]. Bioorg Chem. 2022;120:105647.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• Isoform:

  AChE

• CAS Number:

  [2919335-82-1]