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AChE-IN-74

CAT: 0804-HY-162657Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-162657Size:1 Each
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Description
AChE-IN-74 (Compound 10) is a modulator for cholinesterase. AChE-IN-74 inhibits the proliferation of liver cancer cell Hep3B and SkHep1 with IC50 of 3.6 and 19.9 μM. AChE-IN-74 exhibits a low embryonic toxicity in zebrafish models (10-15 μM) [1].
UNSPSC
12352101
Target
Cholinesterase (ChE)
Type
Reference compound
Related Pathways
Neuronal Signaling
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/anticancer-agent-234.html
Smiles
O=C(N1C2=C(C=CC=C2)SC3=CC=C(Cl)C=C13)CN4CCN(CC5=CC=C(OC)C=C5)CC4
Molecular Formula
C26H26ClN3O2S
Molecular Weight
480.02
References & Citations
[1]Kisla M M, et al. Synthesis and Structure of Novel Phenothiazine Derivatives, and Compound Prioritization via In Silico Target Search and Screening for Cytotoxic and Cholinesterase Modulatory Activities in Liver Cancer Cells and In Vivo in Zebrafish[J]. ACS Omega, 2024.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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Alternative Products

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T210070-01AChE-IN-74
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