MMP-9-IN-8

• UNSPSC Description:

  MMP-9-IN-8 (Compound 3) is an MMP-9 inhibitor with inhibitory activities of 42.16% and 58.28% at 10 μM and 50 μM concentrations, respectively. MMP-9-IN-8 has anti-cancer activity and can induce apoptosis in MCF-7 cells with an IC50 value of 23.42 μM[1].

• Target Antigen:

  Others

• Type:

  Reference compound

• Related Pathways:

  Others

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/mmp-9-in-8.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C(NC1=CC=C(C(C(F)(F)F)=C1)F)NC2=NC(N3CCN(CC3)C)=C(C=CN4C)C4=N2

• Molecular Weight:

  451.42

• References & Citations:

  [1]Kilic-Kurt Z, et al. Effects of pyrrolopyrimidine derivatives on cancer cells cultured in vitro and potential mechanism. Naunyn Schmiedebergs Arch Pharmacol. 2023 Oct 28.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  2490543-89-8