MMP-9-IN-8

MMP-9-IN-8

• CAS Number: 2490543-89-8
• UNSPSC Description: MMP-9-IN-8 (Compound 3) is an MMP-9 inhibitor with inhibitory activities of 42.16% and 58.28% at 10 μM and 50 μM concentrations, respectively. MMP-9-IN-8 has anti-cancer activity and can induce apoptosis in MCF-7 cells with an IC50 value of 23.42 μM[1].
• Target Antigen: Others
• Type: Reference compound
• Related Pathways: Others
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/mmp-9-in-8.html
• Solubility: 10 mM in DMSO
• Smiles: O=C(NC1=CC=C(C(C(F)(F)F)=C1)F)NC2=NC(N3CCN(CC3)C)=C(C=CN4C)C4=N2
• Molecular Weight: 451.42
• References & Citations: [1]Kilic-Kurt Z, et al. Effects of pyrrolopyrimidine derivatives on cancer cells cultured in vitro and potential mechanism. Naunyn Schmiedebergs Arch Pharmacol. 2023 Oct 28.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported