MMP-9-IN-9

MMP-9-IN-9

• CAS Number: 206549-55-5
• UNSPSC Description: MMP-9-IN-9 (compound 4f) is a slective MMP-9 inhibitor with an IC50 of 5 nM. MMP-9-IN-9 shows selective for MMP-9 over MMP-1 and MMP-13. MMP-9-IN-9 shows strong anti-inflammatory and neuroprotective effects[1].
• Target Antigen: MMP
• Type: Reference compound
• Related Pathways: Metabolic Enzyme/Protease
• Applications: COVID-19-immunoregulation
• Field of Research: Inflammation/Immunology; Neurological Disease
• Assay Protocol: https://www.medchemexpress.com/mmp-9-in-9.html
• Purity: 97.0
• Solubility: DMSO : 25 mg/mL (ultrasonic;warming)
• Smiles: O=C(C1=CC(CN(CC)CC)=CC(C)=C1N(S(=O)(C2=CC=C(C=C2)OC)=O)CC3=CC=CC=C3)NO
• Molecular Weight: 511.63
• References & Citations: [1]Eun-Jung Lee, et al. Comparison of the Effects of Matrix Metalloproteinase Inhibitors on TNF-α Release from Activated Microglia and TNF-α Converting Enzyme Activity. Biomol Ther (Seoul). 2014 Sep;22(5):414-9.|[2]J I Levin, et al. The discovery of anthranilic acid-based MMP inhibitors. Part 2: SAR of the 5-position and P1(1) groups. Bioorg Med Chem Lett. 2001 Aug 20;11(16):2189-92.
• Shipping Conditions: Blue Ice
• Storage Conditions: -20°C, 3 years (Powder)
• Clinical Information: No Development Reported