Products for Research Use Only

MMP-9-IN-12

CAT: 0931-T212289-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T212289-01Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
ROS, MMP, Apoptosis
Related Pathways
Apoptosis, Immunology/Inflammation, Proteases/Proteasome
Bioactivity
MMP-9-IN-12 is an inhibitor of matrix metalloproteinase-9 (MMP-9) with an IC50 value of 6.57 μM. It demonstrates an IC50 of 1.54 μM in HCT-116 cells and can induce apoptosis, reactive oxygen species (ROS) generation, and mitochondrial depolarization. Additionally, MMP-9-IN-12 inhibits cell migration and disrupts cell cycle progression, making it useful for colorectal cancer (CRC) research.
Shipping Conditions
Ice Packs
Storage Temperature
-20°C