MMP-2/MMP-9-IN-1

• Product Name Alternative:

  Tyrphostin B66; AG 528

• UNSPSC Description:

  MMP-2/MMP-9-IN-1 is a highly selective, orally active and potent type IV collagenase (MMP-9 and MMP-2) inhibitor with IC50s of 0.24 and 0.31 μM for MMP-9 and MMP-2, respectively. MMP-2/MMP-9-IN-1 is orally active in animal models of tumor growth and metastasis. MMP-2/MMP-9-IN-1 can be used for the research of cancer[1].

• Target Antigen:

  MMP

• Type:

  Reference compound

• Related Pathways:

  Metabolic Enzyme/Protease

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/mmp-2-mmp-9-in-1.html

• Purity:

  99.25

• Solubility:

  10 mM in DMSO

• Smiles:

  OC([C@@H](CC1=CC=CC=C1)NS(C2=CC=C(C3=CC=CC=C3)C=C2)(=O)=O)=O

• Molecular Weight:

  381.44

• References & Citations:

  [1]Y Tamura, et al. Highly selective and orally active inhibitors of type IV collagenase (MMP-9 and MMP-2): N-sulfonylamino acid derivatives. J Med Chem. 1998 Feb 12;41(4):640-9.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  4°C (Powder, protect from light)

• Clinical Information:

  No Development Reported

• CAS Number:

  193807-58-8