Login

MMP-9-IN-5

CAT:
804-HY-146218
Size:
Inquire
Price:
Ask
For price, please contact [email protected]
  • Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
  • Dry Ice Shipment: No
MMP-9-IN-5 - image 1

MMP-9-IN-5

  • CAS Number: 2581824-80-6
  • UNSPSC Description: MMP-9-IN-5 is a MMP-9 inhibitor (IC50: 4.49 nM) that forms hydrogen bond with MMP-9. MMP-9-IN-5 also inhibits AKT activity (IC50: 1.34 nM). MMP-9-IN-5 shows cell cytotoxicity and induces cell apoptosis. MMP-9-IN-5 can be used in the research of cancers[1].
  • Target Antigen: Akt; Apoptosis; MMP
  • Type: Reference compound
  • Related Pathways: Apoptosis;Metabolic Enzyme/Protease;PI3K/Akt/mTOR
  • Applications: Cancer-Kinase/protease
  • Field of Research: Cancer
  • Assay Protocol: https://www.medchemexpress.com/mmp-9-in-5.html
  • Solubility: 10 mM in DMSO
  • Smiles: O=C(C(N(C1=CC=CC=C1)C(C2=C(I)C=CC=C2)=O)C3=CC=CC=C3)NC4=CC=C(C=C4)[N+]([O-])=O
  • Molecular Weight: 577.37
  • References & Citations: [1]Mohammed Salah Ayoup, et al. Battle tactics against MMP-9; discovery of novel non-hydroxamate MMP-9 inhibitors endowed with PI3K/AKT signaling attenuation and caspase 3/7 activation via Ugi bis-amide synthesis. Eur J Med Chem. 2020 Jan 15;186:111875.
  • Shipping Conditions: Room temperature
  • Clinical Information: No Development Reported