GSPT1 degrader-4

• CAS Number:

  3034764-32-1

• UNSPSC Description:

  GSPT1 degrader-4 (3) is a GSPT1 molecule glue (DC50 of 25.4 nM), with an IC50 of 39 nM for CAL51 proliferation[1].

• Target Antigen:

  Molecular Glues

• Type:

  Reference compound

• Related Pathways:

  PROTAC

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/gspt1-degrader-4.html

• Smiles:

  CC1=CC=C(NC(OCC2=CC=C3C(C=C(CN4C5C(NC(CC5)=O)=O)N3C4=O)=C2)=O)C=C1Cl

• Molecular Weight:

  480.90

• References & Citations:

  [1]Jinghai, Jin, et al. Fused ring compound, pharmaceutical composition, and use thereof. Patent. WO2024067792A1.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported