GSPT1 degrader-4

GSPT1 degrader-4

• CAS Number: 3034764-32-1
• UNSPSC Description: GSPT1 degrader-4 (3) is a GSPT1 molecule glue (DC50 of 25.4 nM), with an IC50 of 39 nM for CAL51 proliferation[1].
• Target Antigen: Molecular Glues
• Type: Reference compound
• Related Pathways: PROTAC
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/gspt1-degrader-4.html
• Smiles: CC1=CC=C(NC(OCC2=CC=C3C(C=C(CN4C5C(NC(CC5)=O)=O)N3C4=O)=C2)=O)C=C1Cl
• Molecular Weight: 480.90
• References & Citations: [1]Jinghai, Jin, et al. Fused ring compound, pharmaceutical composition, and use thereof. Patent. WO2024067792A1.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported