HIV-1 protease-IN-10

HIV-1 protease-IN-10

• CAS Number: 2982527-11-5
• UNSPSC Description: HIV-1 protease-IN-10 (Compound 2) has HIV-1 latency reversing activity (IC50: 0.22 μM). HIV-1 protease-IN-10 binds to the PKCδ C1b domain (IC50: 0.69 μM). HIV-1 protease-IN-10 has stability against esterase-mediated hydrolysis[1].
• Target Antigen: HIV; PKC
• Type: Reference compound
• Related Pathways: Anti-infection;Epigenetics;TGF-beta/Smad
• Applications: COVID-19-anti-virus
• Field of Research: Infection
• Assay Protocol: https://www.medchemexpress.com/hiv-1-protease-in-10.html
• Solubility: 10 mM in DMSO
• Smiles: O=C1OC(CO)(COC(C(CCCCCC)CCCCCC)=O)C/C1=C(C)/C
• Molecular Weight: 396.56
• References & Citations: [1]Ishii T, et al. Synthesis and evaluation of DAG-lactone derivatives with HIV-1 latency reversing activity. Eur J Med Chem. 2023 Aug 5;256:115449.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported