HIV-1 protease-IN-12

HIV-1 protease-IN-12

• CAS Number: 2925287-59-6
• UNSPSC Description: HIV-1 protease-IN-12 (compound 35b) is a HIV-1 protease inhibitor with an IC50 of 0.51 nM. HIV-1 protease-IN-12 also inhibits drug-resistant variant[1].
• Target Antigen: HIV Protease
• Type: Reference compound
• Related Pathways: Anti-infection;Metabolic Enzyme/Protease
• Applications: COVID-19-anti-virus
• Field of Research: Infection
• Assay Protocol: https://www.medchemexpress.com/hiv-1-protease-in-12.html
• Solubility: 10 mM in DMSO
• Smiles: O=C(N[C@@H](CC1=CC=CC=C1)[C@H](O)CN(CC(C)C)S(=O)(C2=CC=C(C=C2)O)=O)[C@H]3CCNC3
• Molecular Weight: 489.63
• References & Citations: [1]Huiyu Zhou, et al. Design, synthesis, and biological evaluation of novel HIV-1 protease inhibitors containing pyrrolidine-derived P2 ligands to combat drug-resistant variant. Eur J Med Chem. 2023 Jul 5;255:115389.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported