HIV protease-IN-1

• UNSPSC Description:

  HIV protease-IN-1 (compound 1·succinate) is a potent HIV protease non-peptidic inhibitor, can be used to research AIDS[1].

• Target Antigen:

  HIV Protease

• Type:

  Reference compound

• Related Pathways:

  Anti-infection;Metabolic Enzyme/Protease

• Applications:

  COVID-19-anti-virus

• Field of Research:

  Infection

• Assay Protocol:

  https://www.medchemexpress.com/hiv-protease-in-1.html

• Solubility:

  10 mM in DMSO

• Smiles:

  OC(CCC(O)=O)=O.FC(F)(F)C(C)(C)C[C@@]1(C2=CC=C(C3=NN(C4CC4)N=C3)C=C2)C(N(C(N)=N1)[C@@H](C5=CC(C6=NC=NN6C(F)F)=C(C=C5)Cl)COC(NC7(CC7)C(F)F)=O)=O

• Molecular Weight:

  929.24

• References & Citations:

  [1]Michael A. Ischay, et al. Process Development and Scale-Up of a Protease Inhibitor for the Treatment of HIV Featuring the Preparation of a Neopentyl Grignard Reagent and Development of a One-Pot Curtius Reaction. Org. Process Res. Dev. 2022.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  2511547-82-1