HIV-1 protease-IN-7

HIV-1 protease-IN-7

• CAS Number: 2916441-36-4
• UNSPSC Description: HIV-1 protease-IN-7 (compound 16) is an orally active HIV-1 protease inhibitor (IC50=3.52 nM, EC50=37 nM)[1].
• Target Antigen: HIV Protease
• Type: Peptides
• Related Pathways: Anti-infection;Metabolic Enzyme/Protease
• Applications: COVID-19-anti-virus
• Field of Research: Infection
• Assay Protocol: https://www.medchemexpress.com/hiv-1-protease-in-7.html
• Solubility: 10 mM in DMSO
• Smiles: O=C1N[C@@H](CC(C)C)C(N[C@@H](CCC2CCCCC2)C(N[C@H](C(N([C@H](C(N[C@@H](C)C(N[C@H](C(OC)=O)C(C)(C)SCC(N[C@H](C(N[C@H](C(N3CCC[C@@](C(N[C@H]1C(C)C)=O)3C)=O)C(C)C)=O)CC4=CC=CC=C4)=O)=O)=O)CC5=CC=CC=C5)C)=O)CC(C)C)=O)=O
• Molecular Weight: 1285.68
• References & Citations: [1]Kusumoto Y, et al. Highly Potent and Oral Macrocyclic Peptides as a HIV-1 Protease Inhibitor: mRNA Display-Derived Hit-to-Lead Optimization. ACS Medicinal Chemistry Letters, 2022.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported