Antimalarial agent 28

• Description:

  Antimalarial agent 28 (Compound 2i) is an antiplasmodial agent. Antimalarial agent 28 inhibits P. berghei, with IC50s of 0.561 μM, 0.14 μM, 4.34 μM for Liver stage, early gametocytes and ring stages of P. falciparum[1].

• UNSPSC:

  12352005

• Target:

  Parasite

• Type:

  Reference compound

• Related Pathways:

  Anti-infection

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Infection

• Assay Protocol:

  https://www.medchemexpress.com/antimalarial-agent-28.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C(NCCCCNC1=CC(OC)=CC2=CC3=CC=C(Cl)C=C3N=C12)/C=C/C4=CC=CC(F)=C4

• Molecular Formula:

  C27H25ClFN3O2

• Molecular Weight:

  477.96

• References & Citations:

  [1]Fonte M, et al. New 4- (N-cinnamoylbutyl) aminoacridines as potential multi-stage antiplasmodial leads. Eur J Med Chem. 2023 Oct 5;258:115575.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  [9007-83-4]