SOS1-IN-16

SOS1-IN-16

• CAS Number: 2930763-85-0
• UNSPSC Description: SOS1-IN-16 (Comp 54) is a selective inhibitor of SOS1 with an IC50 of 7.2 nM. SOS1-IN-16 has inhibitory activity of CYP3A4 when using testosterone as a substrate, with an IC50 of 8.9μM. SOS1-IN-16 can be used for cancer research[1].
• Target Antigen: Cytochrome P450; Ras
• Type: Reference compound
• Related Pathways: GPCR/G Protein;MAPK/ERK Pathway;Metabolic Enzyme/Protease
• Applications: Cancer-Kinase/protease
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/sos1-in-16.html
• Solubility: 10 mM in DMSO
• Smiles: C[C@H](C1=C(C(C(F)(F)CO)=CC=C1)F)NC2=NC(C)=NC3=C2C=C(C4=CC(CC(N(C)C)=O)=C(C=C4)OC)C=C3
• Molecular Weight: 552.59
• References & Citations: [1]Chen SJ, et.al.Polysubstituted benzazepine heteroaryl derivative and application thereof
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported