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SOS1-IN-6

CAT: 0804-HY-144210Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-144210Size:1 Each
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Description
SOS1-IN-6 (compound 33-P1) is a potent SOS1 inhibitor with IC50s of 14.9 and 73.3 nM for SOS1-G12D and SOS1-G12V, respectively[1].
CAS Number
2751718-88-2
UNSPSC
12352005
Target
Ras; SOS1
Type
Reference compound
Related Pathways
GPCR/G Protein; MAPK/ERK Pathway
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/sos1-in-6.html
Solubility
10 mM in DMSO
Smiles
O[C@H]1CC[C@H](C2=CC3=C(N[C@@H](C4=CC=CC(C(F)F)=C4F)C)N=C(C)N=C3C5=C2OCC5)CC1
Molecular Formula
C26H28F3N3O2
Molecular Weight
471.51
References & Citations
[1]Fused quinazoline derivative, preparation method therefor and application thereof in medicine. WO2021249475A1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
K-Ras

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