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SOS1-IN-9

CAT: 0804-HY-144207Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-144207Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
SOS1-IN-9 is a potent SOS1 inhibitor with an IC50 of 116.5 nM for SOS1-KRAS G12C (WO2022028506A1, compound 302) [1].
CAS Number
2758900-76-2
UNSPSC
12352005
Target
Ras; SOS1
Type
Reference compound
Related Pathways
GPCR/G Protein; MAPK/ERK Pathway
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/sos1-in-9.html
Solubility
10 mM in DMSO
Smiles
CC1=NC(N[C@@H](C2=CC(N)=CC(C(F)(F)F)=C2)C)=C3CN(CCC3=N1)C4CCOCC4
Molecular Formula
C22H28F3N5O
Molecular Weight
435.49
References & Citations
[1]Sos1 inhibitor, pharmaceutical composition containing same, and use therefor. WO2022028506A1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
K-Ras

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