SOS1-IN-9

SOS1-IN-9

• CAS Number: 2758900-76-2
• UNSPSC Description: SOS1-IN-9 is a potent SOS1 inhibitor with an IC50 of 116.5 nM for SOS1-KRAS G12C (WO2022028506A1, compound 302)[1].
• Target Antigen: Ras
• Type: Reference compound
• Related Pathways: GPCR/G Protein;MAPK/ERK Pathway
• Applications: Cancer-Kinase/protease
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/sos1-in-9.html
• Solubility: 10 mM in DMSO
• Smiles: CC1=NC(N[C@@H](C2=CC(N)=CC(C(F)(F)F)=C2)C)=C3CN(CCC3=N1)C4CCOCC4
• Molecular Weight: 435.49
• References & Citations: [1]Sos1 inhibitor, pharmaceutical composition containing same, and use therefor. WO2022028506A1.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported