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Nadolol

CAT: 0804-HY-B0804-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-B0804-01Size:25 mg
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Description
Nadolol (SQ-11725) is a non-selective and orally active β-adrenergic receptors blocker and is a substrate of organic anion transporting polypeptide 1A2 (OATP1A2) . Nadolol has the the potential for high blood pressure, angina pectoris and vascular headaches research[1][2][3].
CAS Number
42200-33-9
Product Name Alternative
SQ-11725
UNSPSC
12352005
Hazard Statement
H315, H319, H335
Target
Adrenergic Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
COVID-19-immunoregulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/nadolol.html
Concentration
10mM
Purity
99.98
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
OC1CC2=C(C(OCC(O)CNC(C)(C)C)=CC=C2)CC1O
Molecular Formula
C17H27NO4
Molecular Weight
309.41
Precautions
H315, H319, H335
References & Citations
[1]Johannes C von Alvensleben, et al. Nadolol for Treatment of Supraventricular Tachycardia in Infants and Young Children. Pediatr Cardiol. 2017 Mar;38 (3) :525-530.|[2]Osamu Abe, et al. Role of (-) -Epigallocatechin Gallate in the Pharmacokinetic Interaction Between Nadolol and Green Tea in Healthy Volunteers. Eur J Clin Pharmacol. 2018 Jun;74 (6) :775-783.|[3]O Vegas, et al. Effects of Antalarmin and Nadolol on the Relationship Between Social Stress and Pulmonary Metastasis Development in Male OF1 Mice. Behav Brain Res. 2009 Dec 14;205 (1) :200-6.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Launched
Isoform
β adrenergic receptor

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